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cff-version: 1.2.0
message: 'To cite package "SimuRg" in publications use:'
type: software
license: MIT
title: 'SimuRg: Building, Fitting and Evaluating PK/PD Models'
version: 0.2.2
doi: 10.32614/CRAN.package.SimuRg
abstract: Provides a unified workflow for building, fitting using external engines,
  and evaluating ordinary differential equation (ODE)-based pharmacokinetic/pharmacodynamic
  (PK/PD) models. Supports generation of estimation scenarios and control files for
  external engines (e.g., 'Monolix'), simulation of models using 'rxode2', and creation
  of goodness-of-fit diagnostics. Includes tools for covariate modeling, virtual population
  design, and local and global sensitivity analyses.
authors:
- family-names: Sokolov
  given-names: Victor
  email: victor.sokolov@msdecisions.tech
  orcid: https://orcid.org/0000-0001-7066-0811
- family-names: Mikhailova
  given-names: Anna
  email: anna.mikhailova@msdecisions.tech
  orcid: https://orcid.org/0009-0007-1547-5200
- family-names: Ugolkov
  given-names: Yaroslav
  email: yaroslav.ugolkov@msdecisions.tech
  orcid: https://orcid.org/0000-0003-3590-7860
- family-names: Pokladyuk
  given-names: Anatoly
  email: anatoly.pokladyuk@msdecisions.tech
  orcid: https://orcid.org/0009-0003-4680-9518
- family-names: Melnikova
  given-names: Alina
  email: alina.melnikova@msdecisions.tech
  orcid: https://orcid.org/0000-0001-9019-0263
- family-names: Kulesh
  given-names: Victoria
  email: victoria.kulesh@msdecisions.tech
  orcid: https://orcid.org/0000-0001-9289-7262
repository: https://ms-decisions.r-universe.dev
repository-code: https://github.com/ms-decisions/SimuRg
commit: 10895220717e9d2a2609af81110595d7837b66c0
url: https://ms-decisions.github.io/SimuRg/
date-released: '2026-10-07'
contact:
- family-names: Mikhailova
  given-names: Anna
  email: anna.mikhailova@msdecisions.tech
  orcid: https://orcid.org/0009-0007-1547-5200