Package 'SimuRg'

Title: Building, Fitting and Evaluating PK/PD Models
Description: Provides a unified workflow for building, fitting using external engines, and evaluating ordinary differential equation (ODE)-based pharmacokinetic/pharmacodynamic (PK/PD) models. Supports generation of estimation scenarios and control files for external engines (e.g., 'Monolix'), simulation of models using 'rxode2', and creation of goodness-of-fit diagnostics. Includes tools for covariate modeling, virtual population design, and local and global sensitivity analyses.
Authors: Victor Sokolov [cph, aut] (ORCID: <https://orcid.org/0000-0001-7066-0811>), Anna Mikhailova [cre, aut] (ORCID: <https://orcid.org/0009-0007-1547-5200>), Yaroslav Ugolkov [aut] (ORCID: <https://orcid.org/0000-0003-3590-7860>), Anatoly Pokladyuk [aut] (ORCID: <https://orcid.org/0009-0003-4680-9518>), Alina Melnikova [aut] (ORCID: <https://orcid.org/0000-0001-9019-0263>), Victoria Kulesh [aut] (ORCID: <https://orcid.org/0000-0001-9289-7262>)
Maintainer: Anna Mikhailova <[email protected]>
License: MIT + file LICENSE
Version: 0.2.2
Built: 2026-10-16 13:00:13 UTC
Source: https://github.com/ms-decisions/simurg

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