Package: SimuRg 0.2.2

Anna Mikhailova

SimuRg: Building, Fitting and Evaluating PK/PD Models

Provides a unified workflow for building, fitting using external engines, and evaluating ordinary differential equation (ODE)-based pharmacokinetic/pharmacodynamic (PK/PD) models. Supports generation of estimation scenarios and control files for external engines (e.g., 'Monolix'), simulation of models using 'rxode2', and creation of goodness-of-fit diagnostics. Includes tools for covariate modeling, virtual population design, and local and global sensitivity analyses.

Authors:Victor Sokolov [cph, aut], Anna Mikhailova [cre, aut], Yaroslav Ugolkov [aut], Anatoly Pokladyuk [aut], Alina Melnikova [aut], Victoria Kulesh [aut]

SimuRg_0.2.2.tar.gz
SimuRg_0.2.2.zip(r-4.7-any)SimuRg_0.2.2.zip(r-4.6-any)SimuRg_0.2.2.zip(r-4.5-any)
SimuRg_0.2.2.tgz(r-4.6-any)SimuRg_0.2.2.tgz(r-4.5-any)
SimuRg_0.2.2.tar.gz(r-4.7-any)SimuRg_0.2.2.tar.gz(r-4.6-any)
SimuRg_0.2.2.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
SimuRg/json (API)

# Install 'SimuRg' in R:

install.packages('SimuRg', repos = c('https://ms-decisions.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/ms-decisions/simurg/issues

Pkgdown/docs site:https://ms-decisions.github.io

On CRAN:

5.59 score 23 scripts 323 downloads 29 exports 167 dependencies

Last updated from:1089522071. Checks:7 WARNING, 1 ERROR, 1 OK. Indexed: yes.

Target	Result	Time	Files	Syslog
linux-devel	WARNING	218
source / vignettes	ERROR	266
linux-release	WARNING	263
macos-release	WARNING	290
macos-oldrel	WARNING	298
windows-devel	WARNING	250
windows-release	WARNING	212
windows-oldrel	WARNING	210
wasm-release	OK	173

Exports:read_smrg_ctrl read_smrg_obj sg_converter sg_covsearch sg_covsens_sim sg_covsens_vis sg_fit sg_globalsens_sim sg_globalsens_vis sg_gof_obpr sg_gof_par_cov sg_gof_par_dist sg_gof_res sg_gof_res_dist sg_gof_tp sg_localsens_sim sg_localsens_vis sg_modbuild sg_modcomp sg_multistart sg_parsum sg_predist_sim sg_predist_vis sg_sim sg_sim_tp sg_translator sg_vpc_sim sg_vpc_vis sg_vpop_est

Dependencies:armadillo4r backports base64enc BH bit bit64 boot broman bslib cachem checkmate class classInt cli clipr clock clue cluster cmm codetools coin commonmark cpp11 cpp4r crayon data.table diagram digest dparser dplyr dqrng dtw dtwclust e1071 farver fastDummies fastmap flexclust FNN fontawesome forcats foreach foreign fs future future.apply generics ggplot2 ggrepel globals glue gower gtable hardhat hms htmltools httpuv inline ipred irlba isoband iterators jquerylib jsonlite KernSmooth labeling later lattice lava lhs libcoin lifecycle listenv lotri lubridate magrittr MASS Matrix matrixStats memoise mime mipfp mirai modeltools multcomp mvtnorm nanonext nnet numbers numDeriv otel parallelly party pillar pkgconfig plyr polspline ppcor PreciseSums prettyunits prodlim progress progressr promises proto proxy purrr qs2 R6 randomForest ranger rappdirs RColorBrewer Rcpp RcppAnnoy RcppArmadillo RcppEigen RcppParallel RcppProgress RcppThread readr recipes reshape2 rex rlang rmutil rpart Rsolnp RSpectra rxode2 rxode2ll S7 sandwich sass scales sensitivity shape shiny shinyjs sitmo sourcetools sparsevctrs SQUAREM StanHeaders stringfish stringi stringr strucchange survival synthpop sys TH.data tibble tidyr tidyselect timechange timeDate truncnorm tzdb utf8 uwot vctrs viridisLite vroom withr xtable zoo

Vignettes and/or manual for this package failed to build, some documents may be unavailable. Please inspect thebuild logs for more information.

Installation | Model calibration | Data specification | Statistical components | Covariates | Reading model calibration results | Goodness-of-fit | Basic GoF plots

Rendered fromSimuRg.Rmdusingknitr::rmarkdown

Last update: 2026-08-31
Started: 2026-07-13

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